Risk Factors


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    we-care
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    Most NETs are sporadic. However, neuroendocrine tumors can be seen in several inherited familial syndromes, including: Multiple Endocrine Neoplasia type 1 (MEN1), Multiple Endocrine Neoplasia type 2 (MEN2), Von Hippel-Lindau (VHL) disease, Neurofibromatosis type 1, Tuberous Sclerosis, Carney Complex, Given these associations, recommendations may include family history evaluation, evaluation for second tumors, and in selected circumstances testing for germline mutations such as for MEN1.

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